Voices

Studies to inspire: What does the future of breast cancer localisation look like?

Which recent clinical studies completely changed your approach to breast surgery? We asked three researching pioneers - Prof. Alastair Thompson, Prof. Carol Benn and Dr. Andreas Karakatsanis - to discuss the papers that inspired their careers.

In the first part of this intimate chat, they discuss a JAMA Surgery paper from December 2023, which suggests a new wire-free and non-radioactive approach to lesion localisation and SLNB, that's demonstrating impressive accuracy using only Sentimag technologies.

As one of the key contributors to this paper, Dr. Karakatsanis explains:

  • Why he’s predominantly interested in trials that show you can do less to achieve better outcomes.
  • How this study proved a complete magnetic approach results in low re-excision rates - in this case less than 3%, on average.
  • How surgeries could be significantly shorter and the time to specimen excision quicker.
  • That technology performance and reliability is key - the wire approach demonstrated significantly more failed localisations than Magseed.
  • Obtaining buy-in across the multidisciplinary team is key. In this study, physicians were more satisfied with the MagTotal approach across the board.

Read the MagTotal paper in full here