Studies to inspire: Innovations in surgical de-escalation

Papers that demonstrate reduced false negative rates and eliminate unnecessary surgery offer significant benefits to patients. But which studies have moved the dial in this space?

In Part 2 of our Fireside Chat with Prof. Alastair Thompson, Prof. Carol Benn and Dr. Andreas Karakatsanis, they discuss the studies they’ve been guided by and involved in, to validate the most impactful approaches for de-escalating surgery.

They discuss: 

  • How targeting the axilla by clipping suspicious nodes provides better insights on nodal status.
  • Early feedback on Magseed TAD from participants involved in the MAGELLAN study.
  • Why axillary surgery risks morbidity, and the importance of continued research to avoid it where possible.
  • The SentiNOT study providing the opportunity to avoid unnecessary SLNB for 80% of high-risk DCIS patients, by using Magtrace.
  • The purpose of the SentiNOT 2.0 trial and the significance of ongoing international collaboration - especially in an RCT setting.

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Watch part one of the discussion here