Clinical data

The Magseed® marker has been clinically proven to be a safe, accurate and effective treatment

Physicians around the world have been able to take back control of their schedules, achieve low re-excision rates and give their patients a better experience with the Magseed® marker. Used in more countries around the world than any other seed technology the Magseed® marker has been subject to numerous regulatory approvals, clinical trials, new product evaluations and appeared in numerous peer-reviewed papers.

Here you can read these clinical assessments in full and see how Magseed® marker compares to alternative technologies.

This study shows that the Magseed® marker can be accurately placed, demonstrates no migration and is detectable in all sizes and depths of breast tissue

Summary

A study to assess the safety and feasibility of the Magseed® marker, specifically migration.

Key points

  • The Magseed® marker was detectable in all breast sizes (maximum 2.6kg)
  • There were no complication or safety issues
  • No Magseed® marker migration was noted

This study shows that the Magseed® marker provides an effective means for preoperative localisation of non-palpable breast lesions

Summary

The initial experience of an academic teaching institute in implementing a Magseed® marker lesion localisation program.

Key points

  • The Magseed® marker was adopted as standard of care after a two week evaluation
  • The first 4 months of Magseed® marker cases are reported on
  • 100% placement and retrieval success
  • Seed placement was extremely accurate
  • Overall 12% re-excision rate

This study shows that Magseed® marker localisation has the potential to replace conventional wire needle localisation

Summary

A retrospective review of 188 patients receiving Magseed® markers for lesion localisation.

Key points

  • 96.7% of Magseed® markers placed accurately first attempt
  • 100% successful Magseed® marker retrieval rate
  • No complications associated with the Magseed® marker

A radiology report on implementing a Magseed® marker program into a large hospital facility

Key points

  • The Magseed® marker allows for decoupling of the localisation and day of surgery
  • The Magseed® marker bypasses regulatory disadvantages associated with radioactive seed localisation
  • The Magseed® marker is 'indestructable', non-radioactive and poses no danger to clinical staff
  • A reduction in OR delays was noted
  • Great radiology flexibility was achieved

A study evaluating early adoption of the Magseed® marker compared to hookwire lesion localisation

Key points

  • 100% intraoperative success for identifying and retrieving Magseed® markers
  • No statistically significant difference between the Magseed® marker and hookwire re-excision rate
  • Study includes the surgeons first Magseed® marker cases
  • The Magseed® marker allowed surgical approach and incision placement independent of the localisation process

This study shows that the Magseed® marker is a safe, easy technique with a short learning curve, with efficient use of clinical resources

Key points

  • No Magseed® marker migration
  • 14.8% re-excision rate overall, over 12 surgeons
  • No re-excisions for invasive carcinoma required
  • Clinicians found Magseed® marker quicker and easier than a wire
  • All Magseed® markers localised, even in very large breasts

This study shows the largest non-radioactive seed series in the world, demonstrating a highly successful Magseed® marker program implementation

Summary

The largest single institution experience of Magseed® marker for operative localization of non-palpable breast lesions to date (page 96)

Key points

  • 810 Magseed® markers placed in 644 patients by 9 radiologists and 6 surgeons
  • 10.7% overall re-excision rate
  • 100% Magseed® marker retrieval rate

This study shows that Magseed® marker localization is a safe, nonradioactive way to accurately localize axillary lymph nodes preoperatively

Key points

  • 35 patients received Magseed® marker node localization
  • 100% surgical success with 97% Magseed® marker retrieval rate
  • One Magseed® marker was misplaced in the OR, however no regulatory issue with magnetic technology

A study demonstrating Magseed® marker efficacy for breast lymph node marking post Neoadjuvant Chemotherapy

Key points

  • 17 different radiologists placed 50 Magseed® markers into clipped lymph nodes
  • 100% placed first attempt, 88% within the node
  • 10 surgeons removed the Magseed® marked node, with 100% retrieval rate
  • Removal of clipped nodes can be accomplished safely and effectively with Magseed® marker localization.

The Magseed® marker is safe and effective for localisation and excision of non-palpable breast lesions

Summary

A single centre study investigating the effectiveness of the Magseed® marker for lesion localisation

Key points

  • 100% surgical retrieval rate of Magseed® markers
  • Multiple Magseed® markers placed and retrieved in a single excision
  • 6.5% re-excision rate
  • No adverse events

A study demonstrating accurate lesion localisation and SLN detection with the combined use of the Magseed® marker and Magtrace® lymphatic tracer

Key points

  • No Magseed® marker migration was noted and low tumour resection volumes were documented (CRR - 1.49)
  • Peritumoral injection of the Magtrace® lymphatic tracer was utilised and all SLNB’s were successful
  • Clinicians reported the method was easier than hook-wire localisation
  • Hospital scheduling was improved

A study showing the combined use of the Magseed® marker and Magtrace® lymphatic tracer for lesion localisation and SLNB

Key points

  • All lesions were successfully excised with tumour-free margins
  • SLNB was successful in all patients
  • The Magtrace® lymphatic tracer was injected subareolar pre or post operatively
  • No interference between the Magseed® marker and Magtrace® lymphatic tracer signals was noted

Additional references

If you would like to read additional literature relating to the Magseed® marker and its safety, effectiveness and clinical results, please get in touch and we will be happy to assist you.