Clinical data
The Magseed® marker has been clinically proven to be a safe, accurate and effective treatment
Physicians around the world have been able to take back control of their schedules, achieve low re-excision rates and give their patients a better experience with the Magseed® marker. Used in more countries around the world than any other seed technology the Magseed® marker has been subject to numerous regulatory approvals, clinical trials, new product evaluations and appeared in numerous peer-reviewed papers.
Here you can read these clinical assessments in full and see how Magseed® marker compares to alternative technologies.
This study shows that the Magseed® marker can be accurately placed, demonstrates no migration and is detectable in all sizes and depths of breast tissue
Summary
A study to assess the safety and feasibility of the Magseed® marker, specifically migration.
Key points
- The Magseed® marker was detectable in all breast sizes (maximum 2.6kg)
- There were no complication or safety issues
- No Magseed® marker migration was noted
This study shows that the Magseed® marker provides an effective means for preoperative localisation of non-palpable breast lesions
Summary
The initial experience of an academic teaching institute in implementing a Magseed® marker lesion localisation program.
Key points
- The Magseed® marker was adopted as standard of care after a two week evaluation
- The first 4 months of Magseed® marker cases are reported on
- 100% placement and retrieval success
- Seed placement was extremely accurate
- Overall 12% re-excision rate
This study shows that Magseed® marker localisation has the potential to replace conventional wire needle localisation
Summary
A retrospective review of 188 patients receiving Magseed® markers for lesion localisation.
Key points
- 96.7% of Magseed® markers placed accurately first attempt
- 100% successful Magseed® marker retrieval rate
- No complications associated with the Magseed® marker
A radiology report on implementing a Magseed® marker program into a large hospital facility
Key points
- The Magseed® marker allows for decoupling of the localisation and day of surgery
- The Magseed® marker bypasses regulatory disadvantages associated with radioactive seed localisation
- The Magseed® marker is 'indestructable', non-radioactive and poses no danger to clinical staff
- A reduction in OR delays was noted
- Great radiology flexibility was achieved
A study evaluating early adoption of the Magseed® marker compared to hookwire lesion localisation
Key points
- 100% intraoperative success for identifying and retrieving Magseed® markers
- No statistically significant difference between the Magseed® marker and hookwire re-excision rate
- Study includes the surgeons first Magseed® marker cases
- The Magseed® marker allowed surgical approach and incision placement independent of the localisation process
This study shows that the Magseed® marker is a safe, easy technique with a short learning curve, with efficient use of clinical resources
Key points
- No Magseed® marker migration
- 14.8% re-excision rate overall, over 12 surgeons
- No re-excisions for invasive carcinoma required
- Clinicians found Magseed® marker quicker and easier than a wire
- All Magseed® markers localised, even in very large breasts
This study shows the largest non-radioactive seed series in the world, demonstrating a highly successful Magseed® marker program implementation
Summary
The largest single institution experience of Magseed® marker for operative localization of non-palpable breast lesions to date (page 96)
Key points
- 810 Magseed® markers placed in 644 patients by 9 radiologists and 6 surgeons
- 10.7% overall re-excision rate
- 100% Magseed® marker retrieval rate
This study shows that Magseed® marker localization is a safe, nonradioactive way to accurately localize axillary lymph nodes preoperatively
Key points
- 35 patients received Magseed® marker node localization
- 100% surgical success with 97% Magseed® marker retrieval rate
- One Magseed® marker was misplaced in the OR, however no regulatory issue with magnetic technology
A study demonstrating Magseed® marker efficacy for breast lymph node marking post Neoadjuvant Chemotherapy
Key points
- 17 different radiologists placed 50 Magseed® markers into clipped lymph nodes
- 100% placed first attempt, 88% within the node
- 10 surgeons removed the Magseed® marked node, with 100% retrieval rate
- Removal of clipped nodes can be accomplished safely and effectively with Magseed® marker localization.
The Magseed® marker is safe and effective for localisation and excision of non-palpable breast lesions
Summary
A single centre study investigating the effectiveness of the Magseed® marker for lesion localisation
Key points
- 100% surgical retrieval rate of Magseed® markers
- Multiple Magseed® markers placed and retrieved in a single excision
- 6.5% re-excision rate
- No adverse events
A study demonstrating accurate lesion localisation and SLN detection with the combined use of the Magseed® marker and Magtrace® lymphatic tracer
Key points
- No Magseed® marker migration was noted and low tumour resection volumes were documented (CRR - 1.49)
- Peritumoral injection of the Magtrace® lymphatic tracer was utilised and all SLNB’s were successful
- Clinicians reported the method was easier than hook-wire localisation
- Hospital scheduling was improved
A study showing the combined use of the Magseed® marker and Magtrace® lymphatic tracer for lesion localisation and SLNB
Key points
- All lesions were successfully excised with tumour-free margins
- SLNB was successful in all patients
- The Magtrace® lymphatic tracer was injected subareolar pre or post operatively
- No interference between the Magseed® marker and Magtrace® lymphatic tracer signals was noted
Additional references
If you would like to read additional literature relating to the Magseed® marker and its safety, effectiveness and clinical results, please get in touch and we will be happy to assist you.