The Magtrace® node marker is a specially-designed non-radioactive tracer for sentinel lymph node biopsies, made up of a material called ‘superparamagnetic iron oxide’ (SPIO).
The Magtrace® node marker is detected using our Sentimag® probe. When the node marker is injected in the breast, it is totally inert. After tissue-massage or enough time for the tracer to migrate to the lymph nodes has passed, it is only when the probe is passed near the axillary site that it becomes detectable.
Tissue-massage is especially advised if the Magtrace® node marker is administered shortly before surgery (20 minutes) and/or the breast size is large.
Learn more about how the Sentimag® probe works here.
This differs from country to country. There are many assessments of node localisation that have shown significant cost savings for the hospital. Follow this link to get in touch with your nearest sales distribution partner directly.
Begin by drawing 2 ml of the Magtrace® node marker via a sterile needle into an appropriate sterile hypodermic syringe and check the quantity.
Administer the Magtrace® node marker by subcutaneous injection into interstitial tissue, and follow with 5 minutes vigorous massage at the injection site. Surgeons should wait at least 20 minutes before attempting transcutaneous measurement of the axilla.
Proceed with the incision only after obtaining a clear transcutaneous signal with the Sentimag® probe. Migration time may be prolonged due to high age, obesity and large cup size.
Subareolar subcutaneous injection is recommended as it:
Yes, and it is recommended that this be done 20 minutes prior to SLNB being attempted.
We have observed several European surgeons who opt for peritumoral injection (see ‘Magtrace clinical data‘ page).
In some patients a peritumoral injection may take longer to migrate to the axilla than a subareolar injection would. Injecting days ahead of surgery will always improve migration regardless of which injection technique chosen.
The number of nodes removed is at the surgeons discretion. Literature on our ‘Magtrace clinical data‘ page shows that the optimal number of nodes removed is three.
In the US SentimagIC study, the number of nodes removed was 2.4. This number will depend upon surgeon technique and preference. We advocate that nodes should be removed in accordance with the 10% rule.
Yes. Several centres now use the products in combination. It is important to note that currently the Sentimag® probe does not distinguish between the signal from a Magseed® marker versus the Magtrace® node marker.
It is sensible to separate the injection site from the area you wish to sense the Magseed® marker transcutaneously. A distance of 2-3 cm will ensure a separate signal for the Magseed® marker is attained.
Between +2 to +30°C under controlled conditions in a way that temperature variations are minimised. Storage is considered optimal in a climatised surrounding at room temperature e.g. in / or next to the operating theatre or other in-house storage.
For some patients, the Magtrace® node marker leaves a brown ‘bruise-like’ colouration that fades over time. See our ‘Magtrace clinical data‘ page to find results data on this point.
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